By Chloe Street and Dave McIntyre
The fire which was described as “well-developed” broke out shortly before midnight on Sunday in Market Street, Adlington, Chorley.
As a precautionary measure around 20 people were evacuated from their homes and sought refuge in a nearby pub.
A dozen fire engines and over a hundred firefighters were at the commercial premises, which is home to a number of industrial units including; a warehouse for storing furnishings, a paint shop and metal recycling facility.
Fire crews have since brought the fire under control.
Commander Jon Charters, from Lancashire Fire and Rescue Service (LFRS), said the fire in the building, which measures about 3,500 square metres, was already “significant” and “well developed” in parts when crews arrived.
The Lancashire Fire and Rescue crews are being supported by The Manchester Fire and Rescue service who placed crews at strategic points around the incident using water towers to bring the blaze under control.
A spokesman for NFF Newbuild, a nearby business which was affected by the blaze, said “It’s shut our factory down and shut our offices.
“Our office staff are back in now and I’m hoping the factory will be open tomorrow, I doubt we’ll get it open today though.”
NFF have given the fire service access to CCTV footage.
Market Street is closed in both directions near the White Bear roundabout, however, the railway line is unaffected.
The cause of the fire is not yet known.